Product: TA319496Caspase-2 antibody
Quantity: 0.1 mg
Synonyms: CASP-2, CASP2, ICH-1 protease, ICH1, NEDD2, Neural precursor cell expressed developmentally down-regulated protein 2
Presentation: Aff – Purified
Clonality: Polyclonal
Host: Rabbit
Isotype:
CAS NO: 204656-20-2Medchemexpress.com
Shipping to: Europe, USA/Canada
Immunogen: A synthetic peptide corresponding to the N-terminus of rat Caspase-2 protein conjugated to Keyhole Limpet Hemocyanin (KLH) through a cysteine residue linker.AA Sequence:M-A-A-S-S-G-R-S-Q-S-S-L-H-R-K-G-L-C-KLHGeneID:12366
Application: This product was assayed against 1.0 µg of immunizing peptide in a standard sandwich ELISA using HRP conjugated Affinity Purified anti-Rabbit IgG [H&L] (Goat) and TMB as a substrate for 30 minutes at room temperature. A working dilution of 1:2,000 to 1:10
Background: Apoptosis occurs during normal cellular development and involves dramatic changes in cellular structure. Disruption of apoptosis may contribute to cancer and other diseases. Caspases are a family of cysteine proteases that are key mediators of programmed
Concentration: 0.67 mg/ml (by UV absorbance at 280 nm)
Storage: Store vial at -20°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. Dilute only prior to immediate use. For extended storage aliquot contents and freeze at -20°C or below.Avoid cycles of freezing and thawin
Buffer System: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01% (w/v) Sodium Azide as preservative.
Preservatives:
State: Liquid (sterile filtred) purified Ig fraction.Aff – Purified
Specifictiy: This affinity purified antibody is directed against rat and mouse caspase-2. The antibody detects long and short forms of the protein. Antiserum was purified against the immunizing peptide. This antibody reacts with mouse and rat caspase-2, but not caspas