Product: TA343129CARD17 / INCA antibody
Quantity: 50 µg
Synonyms: Caspase recruitment domain-containing protein 17, Caspase-1 inhibitor INCA, Inhibitory caspase recruitment domain protein
Presentation: Purified
Clonality: Polyclonal
Host: Rabbit
Isotype: IgG
CAS NO: 1800401-93-7P-glycoprotein inhibitors
Shipping to: Europe, USA/Canada
Immunogen: The immunogen for anti-CARD17 antibody: synthetic peptide directed towards the middle region of human CARD17. Synthetic peptide located within the following region: MDKARALLDSVIRKGAPACQICITYICEEDSHLAGTLGLSAGPTSGNHLT.GeneID:440068
Application: WB
Background: As a regulator of procaspase-1/CASP1 activation, CARD17 is implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. CARD17 inhibits the release of IL1B in response to LPS in monocytes. However, u
Concentration:
Storage:
Buffer System: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 888% sucrose.
Preservatives:
State: Purified
Specifictiy: