Product: TA340505BRS3 (N-term) antibody
Quantity: 50 µg
Synonyms: BRS-3, Bombesin receptor subtype-3
Presentation: Aff – Purified
Clonality: Polyclonal
Host: Rabbit
Isotype:
CAS NO: 54965-24-1 Product: Tamoxifen (Citrate)
Shipping to: Europe, USA/Canada
Immunogen: Synthetic peptide – KLH conjugatedEpitope: N-terminal extracellular domain of HumanGeneID:680Remarks:The immunizing peptide shows 80% identity (93% similarity) with Mouse and 73% identity (80% similarity) with Rat.
Application: Immunohistochemistry on Paraffin Embedded Sections: 8 µg/mlAntigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100°C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween
Background: BRS3 is classified as an Orphan-A Receptor and is highly similar to the bombesin receptors but has a very low affinity for bombesin itself. Mice lacking BRS3 develop metabolic defects and obesity, suggesting that BRS3 may be an important target for obesit
Concentration: 1.0 mg/ml
Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C to -70°C for longer.Avoid repeated freezing and thawing.Shelf life: one year from despatch.
Buffer System: PBS containing 0.09% Sodium Azide as preservative
Preservatives:
State: Liquid purified Ig fractionAff – Purified
Specifictiy: Reacts with Bombesin Receptor Subtype 3 (BRS3; Family: GPCR; Subfamily: Orphan-A)