Product: AP55694PU-SBCAR1 / CRKAS pTyr410 antibody
Quantity: 50 µl
Synonyms: Breast cancer anti-estrogen resistance protein 1, CASS1, CRK-associated substrate, Cas scaffolding protein family member 1, p130cas, p130cas
Presentation: Aff – Purified
Clonality: Polyclonal
Host: Rabbit
Isotype:
CAS NO: 1597403-47-8 Product: ISRIB (trans-isomer)
Shipping to: Worldwide
Immunogen: Peptide sequence around phosphorylation site of tyrosine 410(G-V-Y(p)-A-V) derived from Human p130 Cas (KLH-conjugated)GeneID:9564
Application: Western blot: 1:500~1:1000.Immunohistochemistry on paraffin sections: 1:50~1:100.
Background: Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.
Concentration: 1.0 mg/ml
Storage: Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.Shelf life: one year from despatch.
Buffer System: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Preservatives:
State: Liquid Ig fractionAff – Purified
Specifictiy: The antibody detects endogenous levels of p130 Cas only when phosphorylated at tyrosine 410.