Product Name :
N-DBCO-N-bis(PEG2-C2-acid)
Description:
N-DBCO-N-bis(PEG2-C2-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
2110449-00-6
Molecular Weight:
624.68
Formula:
C33H40N2O10
Chemical Name:
3-{2-[2-(4-{2-azatricyclo[10.4.0.0⁴,⁹]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl}-N-{2-[2-(2-carboxyethoxy)ethoxy]ethyl}-4-oxobutanamido)ethoxy]ethoxy}propanoic acid
Smiles :
OC(=O)CCOCCOCCN(CCOCCOCCC(O)=O)C(=O)CCC(=O)N1CC2=CC=CC=C2C#CC2=CC=CC=C12
InChiKey:
SQZXTKBMAFTQDM-UHFFFAOYSA-N
InChi :
InChI=1S/C33H40N2O10/c36-30(11-12-31(37)35-25-28-7-2-1-5-26(28)9-10-27-6-3-4-8-29(27)35)34(15-19-44-23-21-42-17-13-32(38)39)16-20-45-24-22-43-18-14-33(40)41/h1-8H,11-25H2,(H,38,39)(H,40,41)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Carboplatin} web|{Carboplatin} Cell Cycle/DNA Damage|{Carboplatin} Biological Activity|{Carboplatin} Data Sheet|{Carboplatin} custom synthesis|{Carboplatin} Autophagy}
Shelf Life:
≥12 months if stored properly.{{LB-100} medchemexpress|{LB-100} Phosphatase|{LB-100} Protocol|{LB-100} In stock|{LB-100} manufacturer|{LB-100} Autophagy}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:24982871
Additional information:
N-DBCO-N-bis(PEG2-C2-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 2110449-00-6|Molecular Weight: 624.68|Formula: C33H40N2O10|Chemical Name: 3-{2-[2-(4-{2-azatricyclo[10.4.0.0⁴,⁹]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl}-N-{2-[2-(2-carboxyethoxy)ethoxy]ethyl}-4-oxobutanamido)ethoxy]ethoxy}propanoic acid|Smiles: OC(=O)CCOCCOCCN(CCOCCOCCC(O)=O)C(=O)CCC(=O)N1CC2=CC=CC=C2C#CC2=CC=CC=C12|InChiKey: SQZXTKBMAFTQDM-UHFFFAOYSA-N|InChi: InChI=1S/C33H40N2O10/c36-30(11-12-31(37)35-25-28-7-2-1-5-26(28)9-10-27-6-3-4-8-29(27)35)34(15-19-44-23-21-42-17-13-32(38)39)16-20-45-24-22-43-18-14-33(40)41/h1-8H,11-25H2,(H,38,39)(H,40,41)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|