Omacromolecules 2009, ten:2379400. 16. Stark WJ: Nanoparticles in biological systems. Angew Chem Int Ed Engl 2011, 50:1242258. 17. Limbach LK, Bereiter R, M ler E, Krebs R, G i R, Stark WJ: Removal of oxide nanoparticles inside a model wastewater remedy plant: Influence of agglomeration and surfactants on clearing efficiency. Environ Sci Technol 2008, 42:5828833.18. Lynch I, Cedervall T, Lundqvist M, Cabaleiro-Lago C, Linse S, Dawson KA: The nanoparticle – protein complex as a biological entity; a complicated fluids and surface science challenge for the 21st century. Adv Colloid Interfac 2007, 134:16774. 19. Wilhelm C, Billotey C, Roger J, Pons JN, Bacri JC, Gazeau F: Intracellular uptake of anionic superparamagnetic nanoparticles as a function of their surface coating. Biomaterials 2003, 24:1001011. 20. Jansch M, Stumpf P, Graf CM, R l E, M ler RH: Adsorption kinetics of plasma proteins on ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles. Int J Pharm 2012, 428:12533. 21. Aggarwal P, Hall JB, McLeland CB, Dobrovolskaia MA, McNeil SE: Nanoparticle interaction with plasma proteins because it relates to particle biodistribution, biocompatibility and therapeutic efficacy. Adv. Drug Delivery Rev 2009, 61:42837. 22. Ge C, Du J, Zhao L, Wang L, Liu Y, Li D, Yang Y, Zhou R, Zhao Y, Chai Z, Chen C: Binding of blood proteins to carbon nanotubes reduces cytotoxicity. Proc Natl Acad Sci 2011, 108:169686973. 23. Kittler S, Greulich C, Gebauer JS, Diendorf J, Treuel L, Ruiz L, Gonzalez-Calbet JM, Vallet-Regi M, Zellner R, Koller M, Epple M: The influence of proteins around the dispersability and cell biological activity of silver nanoparticles.BMVC J Mater Chem 2010, 20:51218.Acalabrutinib 24.PMID:23376608 Orts-Gil G, Natte K, Drescher D, Bresch H, Mantion A, Kneipp J, Osterle W: Characterisation of silica nanoparticles before in vitro studies: from main particles to agglomerates. J Nanopart Res 2011, 13:1593604. 25. Treuel L, Nienhaus GU: Toward a molecular understanding of nanoparticle-protein interactions. Biophys Rev 2012, four:13747. 26. Walczyk D, Baldelli-Bombelli F, Monopoli MP, Lynch I, Dawson KA: What the cell `sees’ in bionanoscience. J Am Chem Soc 2010, 132:5761768. 27. Leszczynski J: Bionanoscience: nano meets bio at the interface. Nat Nanotechnol 2010, 5:63334. 28. Moreau JW, Weber PK, Martin MC, Gilbert B, Hutcheon ID, Banfield JF: Extracellular proteins limit the dispersal of biogenic nanoparticles. Science 2007, 316:1600603. 29. Luck M, Pistel KF, Li YX, Blunk T, Muller RH, Kissel T: Plasma protein adsorption on biodegradable microspheres consisting of Poly(D, L-lactide-co-glycolide), Poly(L-lactide) or ABA triblock copolymers containing Poly(oxyethylene)Influence of production process and polymer composition. J Controlled Release 1998, 55:10720. 30. Gref R, Luck M, Quellec P, Marchand M, Dellacherie E, Harnisch S, Blunk TM, Muller RH: `Stealth’ corona core nanoparticles surface modified by polyethylene glycol (PEG): influences from the corona (PEG chain length and surface density) and of the core composition on phagocytic uptake and plasma protein adsorption. Colloids Surf B 2000, 18:30113. 31. Gessner A, Lieske A, Paulke BR, Muller RH: Functional groups on polystyrene model nanoparticles: influence on protein adsorption. J Biomed Mater Res, Part A 2003, 65:31926. 32. Gessner A, Waicz R, Lieske A, Paulke BR, Mader K, Muller RH: Nanoparticles with decreasing surface hydrophobicities: influence on plasma protein adsorption. Int J Pharm 2000, 196:24549. 33. Thode K, L.