Product Name :
m-PEG7-Amine
Description:
m-PEG7-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG7-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
CAS:
170572-38-0
Molecular Weight:
339.43
Formula:
C15H33NO7
Chemical Name:
2,5,8,11,14,17,20-heptaoxadocosan-22-amine
Smiles :
COCCOCCOCCOCCOCCOCCOCCN
InChiKey:
IQQSLHPGFFGOJW-UHFFFAOYSA-N
InChi :
InChI=1S/C15H33NO7/c1-17-4-5-19-8-9-21-12-13-23-15-14-22-11-10-20-7-6-18-3-2-16/h2-16H2,1H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
m-PEG7-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.{{Bethanechol} site|{Bethanechol} GPCR/G Protein|{Bethanechol} Purity & Documentation|{Bethanechol} Formula|{Bethanechol} custom synthesis|{Bethanechol} Autophagy} m-PEG7-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).{{Gossypol} medchemexpress|{Gossypol} Apoptosis|{Gossypol} Protocol|{Gossypol} In Vitro|{Gossypol} supplier|{Gossypol} Epigenetic Reader Domain} |Product information|CAS Number: 170572-38-0|Molecular Weight: 339.43|Formula: C15H33NO7|Synonym:||Chemical Name: 2,5,8,11,14,17,20-heptaoxadocosan-22-amine|Smiles: COCCOCCOCCOCCOCCOCCOCCN|InChiKey: IQQSLHPGFFGOJW-UHFFFAOYSA-N|InChi: InChI=1S/C15H33NO7/c1-17-4-5-19-8-9-21-12-13-23-15-14-22-11-10-20-7-6-18-3-2-16/h2-16H2,1H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:23795974 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.|References:|Iain Mcculloch, et al. N-type conjugated polymers. WO2018211286A1.Products are for research use only. Not for human use.|