Product Name :
HUN51998
Description:
HUN51998, also known as CRMP2-Ubc9-NaV1.7 inhibitor 194, is a CRMP2-Ubc9-NaV1.7 inhibitor. HUN51998 was first reported in patent WO 2018144900, which functioned as a antagonist of small ubiquitin like modifier (SUMO) related modification (SUMOylation) of collapsin response mediator protein 2 (CRMP2) with potential application for the treatment of voltage gated sodium channel 1.7 (Nav1.7) related itch, anosmia, migraine event, and/or pain (e.g., neuropathic pain). This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).
CAS:
2241651-99-8
Molecular Weight:
567.63
Formula:
C34H31F2N3O3
Chemical Name:
(4-(1-(3-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperidin-1-yl)(4-(3-fluorobenzyloxy)-3-methoxyphenyl)methanone
Smiles :
COC1=CC(=CC=C1OCC1=CC(F)=CC=C1)C(=O)N1CCC(CC1)C1=NC2=CC=CC=C2N1CC1=CC(F)=CC=C1
InChiKey:
HDKZBBHJFURFLF-UHFFFAOYSA-N
InChi :
InChI=1S/C34H31F2N3O3/c1-41-32-20-26(12-13-31(32)42-22-24-7-5-9-28(36)19-24)34(40)38-16-14-25(15-17-38)33-37-29-10-2-3-11-30(29)39(33)21-23-6-4-8-27(35)18-23/h2-13,18-20,25H,14-17,21-22H2,1H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Acetamiprid} medchemexpress|{Acetamiprid} Membrane Transporter/Ion Channel|{Acetamiprid} Purity & Documentation|{Acetamiprid} In stock|{Acetamiprid} custom synthesis|{Acetamiprid} Cancer}
Shelf Life:
≥12 months if stored properly.{{(2-Hydroxypropyl)-β-cyclodextrin} web|{(2-Hydroxypropyl)-β-cyclodextrin} {Biochemical Assay Reagents}|{(2-Hydroxypropyl)-β-cyclodextrin} Biological Activity|{(2-Hydroxypropyl)-β-cyclodextrin} Formula|{(2-Hydroxypropyl)-β-cyclodextrin} manufacturer|{(2-Hydroxypropyl)-β-cyclodextrin} Epigenetic Reader Domain}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
HUN51998, also known as CRMP2-Ubc9-NaV1.7 inhibitor 194, is a CRMP2-Ubc9-NaV1.7 inhibitor. HUN51998 was first reported in patent WO 2018144900, which functioned as a antagonist of small ubiquitin like modifier (SUMO) related modification (SUMOylation) of collapsin response mediator protein 2 (CRMP2) with potential application for the treatment of voltage gated sodium channel 1.7 (Nav1.7) related itch, anosmia, migraine event, and/or pain (e.g., neuropathic pain). This product has no formal name at the moment.PMID:34337881 For the convenience of communication, a temporal code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).|Product information|CAS Number: 2241651-99-8|Molecular Weight: 567.63|Formula: C34H31F2N3O3|Chemical Name: (4-(1-(3-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperidin-1-yl)(4-(3-fluorobenzyloxy)-3-methoxyphenyl)methanone|Smiles: COC1=CC(=CC=C1OCC1=CC(F)=CC=C1)C(=O)N1CCC(CC1)C1=NC2=CC=CC=C2N1CC1=CC(F)=CC=C1|InChiKey: HDKZBBHJFURFLF-UHFFFAOYSA-N|InChi: InChI=1S/C34H31F2N3O3/c1-41-32-20-26(12-13-31(32)42-22-24-7-5-9-28(36)19-24)34(40)38-16-14-25(15-17-38)33-37-29-10-2-3-11-30(29)39(33)21-23-6-4-8-27(35)18-23/h2-13,18-20,25H,14-17,21-22H2,1H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: To be determined|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|